Real-time Simulation of Cardiac Excitation Using Hardwareimplemented Cardiac Excitation Modeling

Authors

  • Farhanahani Mahmud UTHM

Keywords:

Hardware-implemented cardiac excitation model, Luo-Rudy phase I model, reentrant

Abstract

In this paper a hardware-implemented cardiac excitation model of a cardiac cell based on Luo-Rudy phase I (LR1) for the action potential (AP) generation in a mammalian cardiac ventricle is proposed to speed up the computational time during the simulation of the cardiac AP conduction. The hardware-implemented cardiac excitation model is designed by using analog circuits and a dsPIC microcontroller that could reproduce timedependent and time-independent nonlinear current-voltage characteristics of six-type of ionic currents in LR1 model. Through the study, real-time simulations of reentrant excitation conduction of cardiac cells are realized by coupling 30 active circuits of the cell models based on a cable model. The real-time simulations of initiation have been performed by the model and they are comparable to those from the LR1 model. Thus, it is conceivable that the hardware-implemented cardiac excitation model may be useful as one of alternative tools toward further understanding of the reentrant mechanisms.

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Author Biography

  • Farhanahani Mahmud, UTHM
    Department of Electronic Engineering,
    Faculty of Electric and Electrical Engineering, Universiti Tun Hussein Onn Malaysia,
    86400 Parit Raja, Batu Pahat, Johor, MALAYSIA.

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Issue

Section

Issue on Electrical and Electronic Engineering

How to Cite

Mahmud, F. (2012). Real-time Simulation of Cardiac Excitation Using Hardwareimplemented Cardiac Excitation Modeling. International Journal of Integrated Engineering, 4(3). https://penerbit.uthm.edu.my/ojs/index.php/ijie/article/view/617